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1

Teratogenic effects of sodium valproate in mice and rats at midgestation and at term

Elena Menegola, Maria L. Broccia, Heinz Nau, Mariangela Prati, Rossana Ricolfi, Erminio Giavini

Journal:

Teratogenesis, Carcinogenesis, and Mutagenesis

Year:

1996

Language:

english

File:

PDF, 2.56 MB

english, 1996

2

Transfer of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) to the mouse embryo and fetus

Heinz Nau, Rolf Bass

Journal:

Year:

1981

Language:

english

File:

PDF, 533 KB

english, 1981

3

Chromatographic analysis of endogenous retinoids in tissues and serum

Carsten K Schmidt, Abraham Brouwer, Heinz Nau

Journal:

Analytical Biochemistry

Year:

2003

Language:

english

File:

PDF, 367 KB

english, 2003

4

All-trans-retinoic acid and all-trans-retinoyl-β-d-glucuronide alter the development of axolotl embryos (Ambystoma mexicanum) in vitro

Renate Krätke, Ralph Rühl, Frank Kirschbaum, Heinz Nau

Journal:

Archives of Toxicology

Year:

2000

Language:

english

File:

PDF, 566 KB

english, 2000

5

Topical Retinaldehyde Increases Skin Content of Retinoic Acid and Exerts Biologic Activity in Mouse Skin.

Didierjean, Liliane, Carraux, Pierre, Grand, Denise, Sass, Jorn Oliver, Nau, Heinz, Saurat, Jean-Hilaire

Journal:

The Journal of Investigative Dermatology

Year:

1996

File:

PDF, 2.22 MB

1996

6

Different behavior of tetracyclines and sulfonamides in sandy soils after repeated fertilization with liquid manure

Gerd Hamscher, Heike Theresia Pawelzick, Heinrich Höper, Heinz Nau

Journal:

Environmental Toxicology and Chemistry

Year:

2005

Language:

english

File:

PDF, 72 KB

english, 2005

7

Analysis of reproductive toxicity and classification of glufosinate-ammonium

Rolf Schulte-Hermann, Gerald N. Wogan, Sir Colin Berry, Nigel A. Brown, Andrew Czeizel, Erminio Giavini, Lewis B. Holmes, Robert Kroes, Heinz Nau, Diether Neubert, Franz Oesch, Tilmann Ott, Olavi Pelk

Journal:

Regulatory Toxicology and Pharmacology

Year:

2006

Language:

english

File:

PDF, 889 KB

english, 2006

8

Valproic Acid-Induced Neural Tube Defects in Mouse and Human: Aspects of Chirality, Alternative Drug Development, Pharmacokinetics and Possible Mechanisms

Heinz Nau, Ralf-Siegbert Hauck, Katharine Ehlers

Journal:

Basic & Clinical Pharmacology & Toxicology

Year:

1991

Language:

english

File:

PDF, 1.18 MB

english, 1991

9

Determination of Persistent Tetracycline Residues in Soil Fertilized with Liquid Manure by High-Performance Liquid Chromatography with Electrospray Ionization Tandem Mass Spectrometry

Hamscher, Gerd, Sczesny, Silke, Höper, Heinrich, Nau, Heinz

Journal:

Analytical Chemistry

Year:

2002

Language:

english

File:

PDF, 119 KB

english, 2002

10

[Handbook of Experimental Pharmacology] Retinoids Volume 139 ||

Nau, Heinz, Blaner, William S.

Year:

1999

Language:

english

File:

PDF, 77.75 MB

english, 1999

11

Cadmium concentrations in milk and blood of smoking mothers

Radisch, Birgit, Luck, Werner, Nau, Heinz

Journal:

Toxicology Letters

Year:

1987

Language:

english

File:

PDF, 362 KB

english, 1987

12

Species Differences in Pharmacokinetics and Drug Teratogenesis

Journal:

Environmental Health Perspectives

Year:

1986

Language:

english

File:

PDF, 3.72 MB

english, 1986

13

5,10-Methylenetetrahydrofolate reductase genotype determines the plasma homocysteine-lowering effect of supplementation with 5-methyltetrahydrofolate or folic acid in healthy young women

Fohr, Iris P, Prinz-Langenohl, Reinhild, Brönstrup, Anja, Bohlmann, Anja M, Nau, Heinz, Berthold, Heiner K, Pietrzik, Klaus

Journal:

American Journal of Clinical Nutrition

Year:

2002

Language:

english

File:

PDF, 96 KB

english, 2002

14

Antibiotics in dust originating from a pig-fattening farm: a new source of health hazard for farmers?

Hamscher, Gerd, Pawelzick, Heike Theresia, Sczesny, Silke, Nau, Heinz, Hartung, Jörg

Journal:

Environmental Health Perspectives

Year:

2003

Language:

english

File:

PDF, 152 KB

english, 2003

15

Retinoid metabolism and transplacental pharmacokinetics in the cynomolgus monkey following a nonteratogenic dosing regimen with all-trans-retinoic acid

Tzimas, Georg, Nau, Heinz, Hendrickx, Andrew G., Peterson, Pamela E., Hummler, Hans

Journal:

Year:

1996

Language:

english

File:

PDF, 1.17 MB

english, 1996

16

Stereoselective dysmorphogenicity of the enantiomers of the valproic acid analogue 2-N-propyl-4-pentynoic acid (4-yn-VPA): Cross-species evaluation in whole embryo culture

Andrews, James E., Ebron-McCoy, Marian T., Bojic, Ursula, Nau, Heinz, Kavlock, Robert J.

Journal:

Year:

1997

Language:

english

File:

PDF, 55 KB

english, 1997

17

Cell motility is inhibited by the antiepileptic compound, valproic acid and its teratogenic analogues

Peter S. Walmod, Andrew Foley, Anton Berezin, Ursula Ellerbeck, Heinz Nau, Elisabeth Bock, Vladimir Berezin

Journal:

Year:

1998

Language:

english

File:

PDF, 349 KB

english, 1998

18

Enantioselective synthesis and teratogenicity of propylisopropyl acetamide, a CNS-active chiral amide analogue of valproic acid

Ofer Spiegelstein, Meir Bialer, Matthias Radatz, Heinz Nau, Boris Yagen

Journal:

Year:

1999

Language:

english

File:

PDF, 115 KB

english, 1999

19

VPA-induced neural tube defects in mice. I. altered metabolism of sulfur amino acids and glutathione

Ryohei Hishida, Heinz Nau

Journal:

Teratogenesis, Carcinogenesis, and Mutagenesis

Year:

1998

Language:

english

File:

PDF, 151 KB

english, 1998

20

Sequenzanalyse von Polypeptiden und Proteinen mit der kombinierten Gaschromatographie-Massenspektrometrie

Journal:

Angewandte Chemie

Year:

1976

File:

PDF, 1.17 MB

1976

21

Sequence Analysis of Polypeptides and Proteins by Combined Gas Chromatography-Mass Spectrometry

Journal:

Angewandte Chemie International Edition

Year:

1976

Language:

english

File:

PDF, 1.19 MB

english, 1976

22

Pharmacokinetics of valproic acid and metabolites in mouse plasma and brain following constant-rate application of the drug and its unsaturated metabolite with an osmotic delivery system

Heinz Nau, Rainer Zierer

Journal:

Biopharmaceutics & Drug Disposition

Year:

1982

Language:

english

File:

PDF, 603 KB

english, 1982

23

Valproic acid pharmacokinetics in the mouse following controlled-release of pharmacologic and toxic doses via novel implantable and refillable drug reservoirs

Heinz Nau, Paul Finley, Jane Williams, Klaus Brendel

Journal:

Biopharmaceutics & Drug Disposition

Year:

1983

Language:

english

File:

PDF, 498 KB

english, 1983

24

Valproic acid and active unsaturated metabolite (2-EN): Transfer to mouse liver following human therapeutic doses

Prof. Dr. Heinz Nau, Wolfgang Loscher

Journal:

Biopharmaceutics & Drug Disposition

Year:

1985

Language:

english

File:

PDF, 357 KB

english, 1985

25

Anticonvulsant valproic acid inhibits cardiomyocyte differentiation of embryonic stem cells by increasing intracellular levels of reactive oxygen species

Lan Na, Maria Wartenberg, Heinz Nau, Jürgen Hescheler, Heinrich Sauer

Journal:

Birth Defects Research Part A: Clinical and Molecular Teratology

Year:

2003

Language:

english

File:

PDF, 438 KB

english, 2003

26

Characterization of oxidized and glucuronidated metabolites of retinol in monkey plasma by thermospray liquid chromatography/mass spectrometry

Christian Eckhoff, Werner Wittfoht, Heinz Nau, William Slikker Jr

Journal:

Biological Mass Spectrometry = Journal of Mass Spectrometry (Wiley)

Year:

1990

Language:

english

File:

PDF, 537 KB

english, 1990

27

Contribution of cellular retinol-binding protein type 1 to retinol metabolism during mouse development

Nicolas Matt, Carsten K. Schmidt, Valérie Dupé, Christine Dennefeld, Heinz Nau, Pierre Chambon, Manuel Mark, Norbert B. Ghyselinck

Journal:

Developmental Dynamics

Year:

2005

Language:

english

File:

PDF, 1.65 MB

english, 2005

28

Retinoids and spermatogenesis: Lessons from mutant mice lacking the plasma retinol binding protein

Norbert B. Ghyselinck, Nadège Vernet, Christine Dennefeld, Norbert Giese, Heinz Nau, Pierre Chambon, Stéphane Viville, Manuel Mark

Journal:

Developmental Dynamics

Year:

2006

Language:

english

File:

PDF, 2.60 MB

english, 2006

29

Determination of Folate Patterns in Mouse Plasma, Erythrocytes, and Embryos by HPLC Coupled with a Microbiological Assay

Susanne Belz, Heinz Nau

Journal:

Analytical Biochemistry

Year:

1998

Language:

english

File:

PDF, 154 KB

english, 1998

30

Single-run analysis of isomers of retinoyl-β-D-glucuronide and retinoic acid by reversed-phase high-performance liquid chromatography

Jörn Oliver Sass, Heinz Nau

Journal:

Journal of Chromatography A

Year:

1994

Language:

english

File:

PDF, 653 KB

english, 1994

31

High-performance liquid chromatographic determination of methotrexate, 7-hydroxymethotrexate, 5-methyltetrahydrofolic acid and folinic acid in serum and cerebrospinal fluid

Susanne Belz, Christine Frickel, Christiane Wolfrom, Heinz Nau, Günter Henze

Journal:

Journal of Chromatography B: Biomedical Sciences and Applications

Year:

1994

Language:

english

File:

PDF, 788 KB

english, 1994

32

Effects of valproate and E-2-en-valproate on functional and morphological parameters of rat liver. II. Influence of phenobarbital comedication

Wolfgang Loscher, Heinz Nau, Ulrich Wahnschaffe, Dagmar Hönack, Chris Rundfeldt, Werner Wittfoht, Ursula Bojic

Journal:

Epilepsy Research

Year:

1993

Language:

english

File:

PDF, 5.36 MB

english, 1993

33

Novel valproic acid derivatives with potent differentiation-inducing activity in myeloid leukemia cells

Hedwig Deubzer, Barbara Busche, Gabi Rönndahl, Daniel Eikel, Martin Michaelis, Jindrich Cinatl, Sandra Schulze, Heinz Nau, Olaf Witt

Journal:

Leukemia Research

Year:

2006

Language:

english

File:

PDF, 725 KB

english, 2006

34

Determination of propoxur residues in eggs by liquid chromatography–diode array detection after treatment of stocked housing facilities for the poultry red mite (Dermanyssus gallinae)

Gerd Hamscher, Beate Prieß, Jörg Hartung, Monika I. Nogossek, Gerhard Glünder, Heinz Nau

Journal:

Analytica Chimica Acta

Year:

2003

Language:

english

File:

PDF, 133 KB

english, 2003

35

Prediction of teratogenic potency of valproate analogues using cerebellar aggregation cultures

Thomas E. Maar, Ursula Ellerbeck, Elisabeth Bock, Heinz Nau, Arne Schousboe, Vladimir Berezin

Journal:

Year:

1997

Language:

english

File:

PDF, 838 KB

english, 1997

36

Direct determination of folate monoglutamates in plasma by high-performance liquid chromatography using an automatic precolumn-switching system as sample clean-up procedure

Christian Wegner, Margit Trotz, Heinz Nau

Journal:

Journal of Chromatography B: Biomedical Sciences and Applications

Year:

1986

Language:

english

File:

PDF, 776 KB

english, 1986

37

Synthesis, high-performance liquid chromatography–nuclear magnetic resonance characterization and pharmacokinetics in mice of CD271 glucuronide

Ralph Rühl, Renate Thiel, Tanja Silke Lacker, Sabine Strohschein, Klaus Albert, Heinz Nau

Journal:

Journal of Chromatography B: Biomedical Sciences and Applications

Year:

2001

Language:

english

File:

PDF, 747 KB

english, 2001

38

Valnoctamide, valpromide and valnoctic acid are much less teratogenic in mice than valproic acid

Matthias Radatz, Katharine Ehlers, Boris Yagen, Meir Bialer, Heinz Nau

Journal:

Epilepsy Research

Year:

1998

Language:

english

File:

PDF, 106 KB

english, 1998

39

Induction of necrosis and apoptosis of neutrophil granulocytes by Streptococcus pneumoniae

G. Zysk, L. Bejo, B. K. Schneider-Wald, R. Nau, H.-P. Heinz

Journal:

Clinical & Experimental Immunology

Year:

2000

Language:

english

File:

PDF, 270 KB

english, 2000

40

Pentyl-4-yn-valproic acid enhances both spatial and avoidance learning and attenuates age-related NCAM-mediated neuroplastic decline within the rat medial temporal lobe

Keith J. Murphy, Gerard B. Fox, Andrew G. Foley, Helen C. Gallagher, Alan O'Connell, Anne-Marie Griffin, Heinz Nau, Ciaran M. Regan

Journal:

Journal of Neurochemistry

Year:

2001

Language:

english

File:

PDF, 699 KB

english, 2001

41

Retinoid Signaling by all-trans Retinoic Acid and all-trans Retinoyl-beta-D-Glucuronide Is Attenuated by Simultaneous Exposure of Human Keratinocytes to Retinol

Zouboulis, Christos C., Seltmann, Holger, Sass, Jorn Oliver, Ruhl, Ralph, Plum, Claudia, Hettmannsperger, Uwe, Blume-Peytavi, Ulrike, Nau, Heinz, Orfanos, Constantin E.

Journal:

The Journal of Investigative Dermatology

Year:

1999

Language:

english

File:

PDF, 748 KB

english, 1999

42

Physiologically based pharmacokinetics of methoxyacetic acid: Dose–effect considerations in C57BL/6 mice

Ellen J. O'flaherty, Heinz Nau, David McCandless, Robert P. Beliles, Claire M. Schreiner, Dr. William J. Scott Jr.

Journal:

Birth Defects Research Part A: Clinical and Molecular Teratology

Year:

1995

Language:

english

File:

PDF, 1.11 MB

english, 1995

43

Transfer of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) via placenta and milk, and postnatal toxicity in the mouse

Heinz Nau, Rolf Baß, Diether Neubert

Journal:

Archives of Toxicology

Year:

1986

Language:

english

File:

PDF, 428 KB

english, 1986

44

Placental transfer of thiamphenicol in the rat

Rolf Bass, Heinz Nau

Journal:

Archives of Toxicology

Year:

1981

Language:

english

File:

PDF, 493 KB

english, 1981

45

Pharmacokinetic aspects of drug effects in vitro: effects of serum protein binding on concentration and teratogenicity of valproic acid and 2-en-valproic acid in whole embryos in culture

Constanze Lewandowski, Stephan Klug, Heinz Nau, Diether Neubert

Journal:

Archives of Toxicology

Year:

1986

Language:

english

File:

PDF, 369 KB

english, 1986

46

Operative treatment and prognosis of syringomyelia

Helmut Wiedemayer, Heinz-Eugen Nau, Friedhelm Rauhut, Wilhelm Grote, Lieselotte Gerhard

Journal:

Neurosurgical Review

Year:

1994

Language:

english

File:

PDF, 601 KB

english, 1994

47

The enantiomers of the teratogenic thalidomide analogue EM 12

Hans-Josef Schmahl, Heinz Nau, Diether Neubert

Journal:

Archives of Toxicology

Year:

1988

Language:

english

File:

PDF, 429 KB

english, 1988

48

Embryotoxic effects of thalidomide derivatives on the non-human primateCallithrix jacchus

Wolfgang Heger, Stephan Klug, Hans-Josef Schmahl, Heinz Nau, Hans-Joachim Merker, Diether Neubert

Journal:

Archives of Toxicology

Year:

1988

Language:

english

File:

PDF, 352 KB

english, 1988

49

Neuropathological findings in lesions of the optic nerve of different etiologies

Volker Reinhardt, Heinz-Eugen Nau, Heinz-Hermann Hugo

Journal:

Neurosurgical Review

Year:

1988

Language:

english

File:

PDF, 629 KB

english, 1988

50

Intramedullary pilocytic astrocytomas — a clinical and morphological study after combined surgical and photon or neutron therapy

Friedhelm Rauhut, Volker Reinhardt, Volker Budach, Helmut Wiedemayer, Heinz-Eugen Nau

Journal:

Neurosurgical Review

Year:

1989

Language:

english

File:

PDF, 399 KB

english, 1989

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